Manna Pro Nurse All Multi-Species Milk Replacer, Powered by Opti-Gut™ to Support Gut Health & Digestion, All-Milk Protein, Easy-To-Mix Formula, 8 Pounds Review
By Dr. Lena Ortiz · Canine wellness writer · Published 2026-06-14 · Updated 2026-06-21
4.6(1,275)Amazon rating$50.44100+ bought last month
Our verdict
Manna Pro Nurse All is an 8 lb multi-species milk replacer built around Opti-Gut for digestive support, and with 1,275 reviews averaging 4.6 stars it's one of the better reviewed large format options for feeding puppies alongside other young animals.
Breeders, farms, or multi-animal households who need a large batch, all-milk-protein replacer that covers puppies among a range of young animals from day 2 through weaning.
Skip if
You only need a small amount for one puppy, since this 8 lb bag is built for higher volume, multi-animal feeding rather than a single small litter.
Form Powder
Flavor Vanilla
Benefits Supports Gut Health, Growth, And Easy Mixing
Best for Digestive Health
Breed size All
Weight 8 Pounds
Priced 94% above the category median ($25.99 across 21 tracked models)
Our scorecard
4.6/5overall
Owner rating4.6/5
4.6 average across 1,275 owner ratings
Popularity3.2/5
1,275 owner reviews, more than most models here
The overall score is owner satisfaction weighted by how many reviews back it, so a high rating from few reviews counts for less. The bars below show where this model stands against the other dog food and health supplements we track in this category on price, popularity and size. Context, not marks against it, and our read of the data, not a lab test.
Overview
["This 8 lb bag of Manna Pro Nurse All is built around what the brand calls Opti-Gut, aimed at supporting gut health and digestion, and it's formulated with all-milk protein in a vanilla flavored powder. The recommended uses explicitly list puppies among calves, foals, goat kids, lambs, piglets, llamas, and alpacas, all from day 2 through weaning, making this a genuinely multi-species product rather than a dog-specific one repackaged for pets.", "Manna Pro lists supporting gut health, growth, and easy mixing as the core benefits, and the formula includes a probiotic. It's rated for all breed sizes and covers the full age range described on the label.", "At $50.44 for 8 lb, or 128 oz, it's the priciest option in this set, but the large format and multi-species versatility can make sense for anyone feeding more than just a puppy or two. With 1,275 reviews and a 4.6 star average, it's also one of the more reviewed products here."]
Pros
Formulated with all-milk protein and a probiotic for gut support
Large 8 lb bag suited to higher volume or multi-animal feeding
Manna Pro lists easy mixing as a benefit
Strong 4.6 star average across over 1,200 reviews
Cons
Highest price point among the milk replacers reviewed here
Multi-species formula means it's not exclusively optimized for puppies
Large bag size is impractical if you only need to feed a single small litter
Specifications
Form
Powder
Flavor
Vanilla
Benefits
Supports Gut Health, Growth, And Easy Mixing
Best for
Digestive Health
Breed size
All
Weight
8 Pounds
Performance notes
The Opti-Gut branding points to a digestion focused formula, and pairing an all-milk protein base with a probiotic is consistent with that goal. Because the recommended uses span several species from day 2 through weaning, the formula reads as a general purpose young animal replacer rather than one tuned specifically to puppy needs, which is worth knowing if you want the most puppy-targeted option available.
What buyers say
Over 1,200 reviews at a 4.6 star average is a strong, well established result for a large format milk replacer, suggesting it holds up across the many different animals and use cases it's marketed for.
No, Manna Pro markets this as a multi-species replacer for young animals including calves, foals, goat kids, lambs, piglets, llamas, alpacas, puppies, and kittens, so puppies are one of several intended uses.
What does Opti-Gut mean?
It's Manna Pro's name for the gut health focused blend in this formula, paired with an all-milk protein base and a probiotic, according to the product listing.
Is the 8 lb size too much for a single puppy?
It can be more than a small litter needs. This size is built for higher volume or multi-animal feeding, so a smaller puppy-specific container may be more practical for just one or two puppies.
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