4.7(68)Amazon rating$15.993,000+ bought last month
Our verdict
OptixCare's Eye Lube Plus is a sterile, hyaluronic acid based lubricating gel sized at 20 grams, built for flexible, as-needed moisture relief, and it's the strongest overall performer in this eye care lineup on both rating and monthly purchase volume.
Dogs with dry or irritated eyes who need routine lubrication drops, especially since dosing is flexible, described as 1 to 2 drops as often as needed or as directed by your vet.
Skip if
You're looking for a medicated treatment for an infection or injury rather than a plain lubricant, since this is formulated for moisture and comfort, not for treating disease.
Weight 20 Grams
Priced 11% below the category median ($17.99 across 53 tracked models)
Our scorecard
4.4/5overall
Owner rating4.7/5
4.7 average across 68 owner ratings
Popularity0.7/5
68 owner reviews, fewer than most models here
The overall score is owner satisfaction weighted by how many reviews back it, so a high rating from few reviews counts for less. The bars below show where this model stands against the other dog food and health supplements we track in this category on price, popularity and size. Context, not marks against it, and our read of the data, not a lab test.
Overview
OptixCare Eye Lube Plus (model OPX-4252) is a 20 gram sterile lubricant containing hyaluronic acid, made by Aventix Animal Health Corp and labeled for dogs, cats, horses, and other small animals. Dosing is 1 to 2 drops in one or both eyes, administered as often as needed or as directed by a veterinarian, and the packaging stays sterile until the cap is first removed.
Priced at $15.99, it's also the least expensive product in this comparison, yet it carries the highest rating of the group at 4.7 stars from 68 reviews, along with by far the largest purchase volume, around 3,000 units in the past month.
Because it's a lubricant rather than a targeted treatment, it's best suited to ongoing comfort and moisture support. Any dog with a suspected infection, injury, or chronic eye condition should still see a vet for a proper diagnosis rather than relying on a lubricant alone.
Pros
Highest rating in this comparison at 4.7 stars from 68 reviews
By far the most purchased of the five products, around 3,000 units in the past month
Contains hyaluronic acid, a moisture-focused ingredient
Sterile packaging until first use
Flexible dosing, "as often as needed," per the directions
Lowest price point of the group at $15.99
Cons
It's a lubricant, not a treatment, so it won't resolve an underlying infection or condition
20 gram size may need reordering with frequent daily use in multi-dog households
Specifications
Weight
20 Grams
Performance notes
Formulated as a lubricating gel containing hyaluronic acid, packaged sterile at 20 grams, with dosing of 1 to 2 drops per eye as needed or as directed by a veterinarian; labeled for dogs, cats, horses, and small animals.
What buyers say
A 4.7 star average across 68 reviews paired with roughly 3,000 units bought in the past month makes this the clear standout of the group for real-world demand and satisfaction.
Hyaluronic acid is generally used in eye lubricants for its moisture-retaining properties, which is formulated to support comfort in dry or irritated eyes rather than to treat an underlying disease.
How often can I use it?
The directions allow 1 to 2 drops in one or both eyes as often as needed, or as directed by your veterinarian, giving more flexibility than products with a strict daily schedule.
Is it safe for cats and other pets too?
Per the label it's meant for dogs, cats, horses, and small animals, though you should always confirm with your vet before using any eye product across multiple types of pets.
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