Now Pets, UC-II® Advanced Joint Mobility for Dogs and Cats, Veterinarian formulated, Help Maintain Cartilage and Connective Tissue*, 60 Chewable Tablets (60 Grams) Review
By Marcus Bell · Dog nutrition editor · Published 2026-05-18 · Updated 2026-06-27
4.3(170)Amazon rating$19.161,000+ bought last month
Our verdict
Now Pets UC-II Advanced Joint Mobility is a veterinarian formulated chew built around undenatured type II collagen (UC-II), a single targeted ingredient rather than a broad multi ingredient blend, and it is positioned to help maintain cartilage and connective tissue in both dogs and cats.
Owners who want a simple, single ingredient UC-II collagen chew rather than a multi ingredient joint blend, for dogs or cats in a shared household.
Skip if
You want a broader formula that also includes glucosamine, chondroitin, or omega fatty acids, since this product centers on UC-II collagen alone.
Priced 42% below the category median ($32.91 across 92 tracked models)
Our scorecard
4.2/5overall
Owner rating4.3/5
4.3 average across 170 owner ratings
Popularity0.4/5
170 owner reviews, fewer than most models here
The overall score is owner satisfaction weighted by how many reviews back it, so a high rating from few reviews counts for less. The bars below show where this model stands against the other dog food and health supplements we track in this category on price, popularity and size. Context, not marks against it, and our read of the data, not a lab test.
Overview
['This 60 count bag of chewable tablets from Now Pets is built around UC-II, a form of undenatured type II collagen that the brand describes as veterinarian formulated. Rather than combining several joint ingredients into one chew, the formula leans on UC-II as its core ingredient, aimed at helping maintain cartilage and connective tissue in dogs and cats.', 'At 60 grams total and a $19.16 price, this is a smaller, lower cost entry point into UC-II based joint support compared to some multi ingredient chews on the market. It suits owners who want to try a single ingredient approach before committing to a larger, more expensive formula.', 'With 170 reviews and a 4.3 star average, plus roughly 1,000 bought in the past month, it has a smaller but generally positive track record compared to some of the bigger names in this category.']
Pros
Built around UC-II, a well studied form of undenatured type II collagen
Veterinarian formulated positioning
Works for both dogs and cats in the same household
Affordable entry price for a UC-II based chew
Cons
Smaller review base (170) than many competing joint chews
Single ingredient focus means no added glucosamine, chondroitin, or omega fatty acids
60 gram size may require frequent reordering for larger dogs
Performance notes
Because this formula centers on UC-II rather than a multi ingredient stack, dosing is simpler and there is less risk of ingredient overlap if your dog is already on another supplement. The chewable tablet format is straightforward, though it lacks the added flavors or soft chew texture some multi ingredient products use to boost palatability.
What buyers say
A 4.3 star average across 170 reviews is a solid but modest sample size, and around 1,000 units bought in the past month suggests steady but not massive demand relative to bigger multi ingredient joint chews in this category.
What is UC-II and how is it different from glucosamine?
UC-II is a form of undenatured type II collagen, a different mechanism than glucosamine or chondroitin. This product uses UC-II as its main ingredient rather than combining it with other joint compounds, so if you want a broader blend you may want to compare formulas.
Can this be given to cats as well as dogs?
The product is marketed for both dogs and cats, based on the label. As with any supplement, check with your vet before starting a new product, especially if your pet has an existing health condition.
Is this a substitute for veterinary care?
No. This is a supplement intended to help maintain cartilage and connective tissue, not a treatment for diagnosed joint disease. If your dog is showing signs of pain or mobility issues, talk to your vet.
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