4.8(1,100)Amazon rating$144.991,000+ bought last month
Our verdict
Hill's Prescription Diet Gastrointestinal Biome is the top seller among veterinary diet dog foods in this lineup, and a 4.8 star rating across roughly 1,145 reviews backs up its reputation for helping settle sensitive stomachs.
Dogs with loose stool or a sensitive stomach whose vet wants a formula built around gut microbiome support.
Skip if
Your dog does not have digestive or stomach sensitivity issues, since this formula is built specifically around that concern.
Form Dry Food
Flavor Chicken
Benefits Helps Firm Loose Stool In 24 Hours, Reduces Recurrence, Promotes Regularity, Supports Microbiome Health
Best for Sensitive Stomach
Breed size Medium
Weight 27.5 Pounds
Priced 77% above the category median ($81.99 across 50 tracked models)
Our scorecard
4.8/5overall
Owner rating4.8/5
4.8 average across 1,100 owner ratings
Popularity4.4/5
1,100 owner reviews, more than most models here
The overall score is owner satisfaction weighted by how many reviews back it, so a high rating from few reviews counts for less. The bars below show where this model stands against the other dog food and health supplements we track in this category on price, popularity and size. Context, not marks against it, and our read of the data, not a lab test.
Overview
This 27.5 lb bag of chicken flavored kibble is built around Hill's ActivBiome plus technology, combining a prebiotic fiber blend with high omega-3 fatty acids to support the gut microbiome. Hill's states it can help firm loose stool within 24 hours and reduce its recurrence while promoting regular digestion.
At $144.99, it is priced in line with other prescription formulas in this category, but it stands out with 4.8 stars across roughly 1,145 reviews and around 1,000 bags bought in the past month, the strongest sales and review numbers in this group.
Pros
ActivBiome+ technology paired with a prebiotic fiber blend
High omega-3 fatty acid content for digestive support
Stated to help firm loose stool and reduce its recurrence
Highest rating in this group at 4.8 stars across roughly 1,145 reviews
Strong recent demand with about 1,000 bags bought last month
Cons
Premium price typical of a prescription veterinary diet
Only useful for dogs with an actual sensitive stomach or digestive issue
Large 27.5 lb bag size may not suit smaller households
Specifications
Form
Dry Food
Flavor
Chicken
Benefits
Helps Firm Loose Stool In 24 Hours, Reduces Recurrence, Promotes Regularity, Supports Microbiome Health
Best for
Sensitive Stomach
Breed size
Medium
Weight
27.5 Pounds
Performance notes
This is a dry kibble in a 27.5 lb bag, chicken flavored, built around a prebiotic fiber blend and dairy free formulation. Hill's markets the ActivBiome+ technology as the core of its digestive and fiber care positioning, alongside a high omega-3 fatty acid profile.
What buyers say
With roughly 1,145 reviews averaging 4.8 stars and about 1,000 bags bought in the last month, this is the best-reviewed and best-selling veterinary diet dog food in this lineup, suggesting strong owner satisfaction for dogs with sensitive stomachs.
ActivBiome+ is Hill's name for a fiber blend formulated to support a healthy gut microbiome, which the brand states helps firm loose stool and promotes regular digestion in dogs with sensitive stomachs.
How quickly does this help with loose stool?
Hill's states the formula is designed to help firm loose stool within 24 hours, though individual results vary and a dog with ongoing digestive issues should be evaluated by a vet.
Is this suitable for every dog?
This is a veterinary diet aimed at dogs with digestive sensitivity, not a general-purpose food. If your dog does not have stomach issues, a standard formula is likely a better fit.
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