Pro Plan Veterinary Diets FortiFlora Chewable Probiotic Tablets for Dogs and Puppies, Digestive Health Support for Occasional Diarrhea Management, 45-Count Review
By Marcus Bell · Dog nutrition editor · Published 2026-06-01 · Updated 2026-06-28
4.7(5,046)Amazon rating$50.0010,000+ bought last month
Our verdict
Purina Pro Plan Veterinary Diets FortiFlora is a liver flavored chewable probiotic tablet built around a single studied strain, Enterococcus faecium SF68, and with 5,046 reviews averaging 4.7 stars and about 10,000 bought last month, it's one of the most widely used probiotics in this entire category.
Dogs and puppies needing digestive support during occasional diarrhea or diet transitions, especially owners who want a widely recommended, veterinarian associated brand.
Skip if
You want a multi strain blend rather than a single strain formula, or your dog needs a longer term maintenance product rather than one aimed at occasional digestive upset.
Form Tablet
Flavor Liver
Best for Digestive Health; Gastrointestinal; Immune Support; Diarrhea; Probiotics
Breed size Large
Weight 2.78 Ounces
Priced 100% above the category median ($24.99 across 128 tracked models)
Our scorecard
4.7/5overall
Owner rating4.7/5
4.7 average across 5,046 owner ratings
Popularity4.3/5
5,046 owner reviews, more than most models here
The overall score is owner satisfaction weighted by how many reviews back it, so a high rating from few reviews counts for less. The bars below show where this model stands against the other dog food and health supplements we track in this category on price, popularity and size. Context, not marks against it, and our read of the data, not a lab test.
Overview
['FortiFlora is built around a single active ingredient, Enterococcus faecium SF68, delivered in a liver flavored chewable tablet. Purina markets it specifically for digestive health, gastrointestinal support, immune support, and management of occasional diarrhea, and the 45 count size is meant for shorter term or as needed use rather than a bulk long term supply.', "As part of Purina's Veterinary Diets line, this product carries the kind of brand recognition that comes with being one of the most recommended chewable probiotics, and the liver flavor is designed to make it easy to give without disguising it in food.", 'At $50.00 for 45 tablets, this is priced at the higher end per tablet, but with 5,046 reviews averaging 4.7 stars and roughly 10,000 units bought in the past month, it has by far the largest and most consistent buyer base of the probiotics covered here.']
Pros
Single studied strain, Enterococcus faecium SF68, in a liver flavored chewable
Extremely large review base, 5,046 reviews at a 4.7 star average
About 10,000 bought last month, the highest volume in this group
Marketed specifically for occasional diarrhea and gastrointestinal support
Part of Purina's Veterinary Diets line, a widely recognized brand
Cons
45 count size is smaller than some bulk probiotic options
Higher price per tablet than multi strain capsule or powder alternatives
Single strain formula rather than a broader multi strain blend
This formula relies on one strain, Enterococcus faecium SF68, at a stated potency of roughly 1x10 to the 8th CFU per gram, rather than combining multiple bacterial species. The liver flavored chewable tablet format is built for palatability, and the 45 count size positions it more for shorter digestive support windows, like diet transitions or occasional loose stool, than for indefinite daily maintenance.
What buyers say
With 5,046 reviews averaging 4.7 stars and an estimated 10,000 units bought in the past month, this is the highest volume, most reviewed probiotic in this lineup, reflecting its position as a widely recommended option.
It's built around a single strain, Enterococcus faecium SF68, delivered as a liver flavored chewable tablet rather than a multi strain blend.
Is this meant for daily long term use or short term issues?
The label markets it toward digestive health, gastrointestinal support, and occasional diarrhea management, and the 45 count size suggests it's often used for shorter support windows, though some owners do use it as an ongoing daily supplement. Ask your vet what fits your dog's situation.
Can puppies take this?
The title lists both dogs and puppies, but as with any supplement, check with your vet on appropriate use for a puppy's age and size.
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