Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats Without Hydrocortisone, 1.25oz Review

4.6 (1,600) Amazon rating$29.99300+ bought last month

Our verdict

This is the hydrocortisone-free version of Zymox's Otic Plus enzymatic ear solution, aimed at owners who want the brand's enzymatic approach without a steroid in the mix, and a 4.6 star average across 1,600 reviews backs its reputation.

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Best for

Dogs that need help with ear irritation, whose owners or vets prefer to avoid hydrocortisone in the ear.

Skip if

Your dog has a punctured eardrum, since the label specifically warns against use in that case, or your vet has recommended a formula with a steroid for faster inflammation relief.

  • Weight 0.01 Ounces
  • Priced 77% above the category median ($16.99 across 63 tracked models)

Our scorecard

4.6/5 overall
  • Owner rating4.6/5

    4.6 average across 1,600 owner ratings

  • Popularity3.2/5

    1,600 owner reviews, more than most models here

The overall score is owner satisfaction weighted by how many reviews back it, so a high rating from few reviews counts for less. The bars below show where this model stands against the other dog food and health supplements we track in this category on price, popularity and size. Context, not marks against it, and our read of the data, not a lab test.

Overview

["This 1.25 oz solution is applied directly to the uncleaned ear, filling the canal, gently massaged in, then wiped of excess, once daily for 7 days, or 14 days for chronic issues. It's built without hydrocortisone, positioning it as the steroid-free option in Zymox's Otic Plus line.", "The label notes it's safe for extended use on persistent cases, though it should not be used on a punctured eardrum. Directions are simple, a single daily application rather than multiple doses spread through the day.", 'At $29.99, it costs more than a basic cleaning rinse, and with about 300 units bought last month and 1,600 reviews averaging 4.6 stars, it holds a solid track record within the established Zymox enzymatic line.']

Pros

  • Steroid-free option for owners avoiding hydrocortisone
  • Simple once-daily application
  • No need to pre-clean the ear before applying
  • Labeled safe for extended use in persistent cases
  • Backed by the established Zymox enzymatic line and a 4.6 star rating

Cons

  • Pricier than basic ear cleaning rinses at $29.99 for 1.25 oz
  • Not for use on a punctured eardrum
  • No detailed ingredient breakdown beyond the enzymatic, hydrocortisone-free framing

Specifications

Weight
0.01 Ounces

Performance notes

The single daily application goes directly onto the uncleaned ear, filling the canal before massaging and wiping away excess, following a 7-day course that can extend to 14 days for chronic issues, with the label noting it's safe for continued extended use in persistent cases.

What buyers say

1,600 reviews at a 4.6 star average, with about 300 units bought in the past month, put this in line with other well-established Zymox ear care products, though it isn't the top seller in the lineup here.

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Frequently asked questions

Do I need to clean my dog's ear before applying this?

No, directions say to apply directly to the uncleaned ear, filling the canal, then massage and wipe away any excess.

How long should I use it?

The standard course is once daily for 7 days, extending to 14 days for chronic issues, and the label notes it's safe for extended use in persistent cases.

Does this contain hydrocortisone?

No, this is the hydrocortisone-free version of Zymox's Otic Plus formula, for owners who want to avoid a steroid component.

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