4.6(2,538)Amazon rating$23.49300+ bought last month
Our verdict
Zymox Otic Enzymatic Solution is a hydrocortisone-free, once-a-day ear drop built around an enzyme system meant to target the bacteria and yeast behind common ear irritation, and its 4.6 star average across 2,538 reviews points to strong owner satisfaction.
Dogs dealing with recurring ear irritation who need a no-cleaning-required daily drop and owners who want to avoid hydrocortisone.
Skip if
Your dog needs steroid based itch relief alongside the enzyme-based solution, or the ear issue hasn't improved after a week or two, since that calls for a vet exam rather than more at-home product.
Weight 1.6 Ounces
Priced 38% above the category median ($16.99 across 63 tracked models)
Our scorecard
4.6/5overall
Owner rating4.6/5
4.6 average across 2,538 owner ratings
Popularity3.7/5
2,538 owner reviews, more than most models here
The overall score is owner satisfaction weighted by how many reviews back it, so a high rating from few reviews counts for less. The bars below show where this model stands against the other dog food and health supplements we track in this category on price, popularity and size. Context, not marks against it, and our read of the data, not a lab test.
Overview
["This 1.25 oz Zymox Otic Enzymatic Solution is labeled for all life stages and is the version without added hydrocortisone. It's applied directly to an unwashed ear rather than requiring a separate cleaning step first, then massaged in and allowed to work while your dog shakes out the excess.", "The formula is built on an enzyme system designed to help target the bacteria and yeast associated with common ear irritation, applied once daily for about a week in typical cases, with the option to continue longer for more stubborn cases. This is a topical management product, not a substitute for a veterinary diagnosis, so it's worth checking in with a vet if things don't improve within that window.", "At $23.49 for a 1.25 oz bottle, it sits in the mid range for this category, and with 2,538 reviews holding a 4.6 star average and roughly 300 units bought in the past month, it's a well established option under the Pet King Brands Zymox line."]
Pros
No pre-cleaning required, so it applies straight to an unwashed ear
Once-daily dosing for about a week makes it simple to stick with
Hydrocortisone-free formula for owners who prefer to avoid steroids
Strong 4.6 star rating across over 2,500 reviews
Cons
A full course runs about a week or longer, so it isn't an instant fix
For external use only, so it won't help with issues that need veterinary attention
Limited independent detail beyond the brand's own labeling
Specifications
Weight
1.6 Ounces
Performance notes
This solution is meant for topical, external application only. You apply it to an unwashed ear, massage it in, and let your dog shake out the excess rather than wiping the ear clean first. The label calls for once-daily use for about 7 days in typical cases, with owners advised to check in with a vet if irritation doesn't ease up in that time, since this is a topical management product and not a substitute for a veterinary diagnosis.
What buyers say
With 2,538 reviews holding at a 4.6 star average and roughly 300 units bought in the past month, this is a well established, steady seller in the ear care category rather than a newcomer.
Do I need to clean my dog's ear before applying this?
No, the directions call for applying it to an unwashed ear, filling the canal and massaging it in, then letting your dog shake out any excess. No separate cleaning step is needed beforehand.
Is this the same as the version with hydrocortisone?
No, this is the version without hydrocortisone. Pet King Brands also sells a version of this Otic solution with 1% hydrocortisone for added itch relief if your dog needs that extra support.
What if my dog's ear doesn't improve after using this?
If irritation doesn't ease up within about a week of daily use, it's a good idea to see a vet rather than continuing to rely on an at-home product alone, since ongoing irritation can point to something that needs a professional look.
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